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. Author manuscript; available in PMC: 2010 Jul 7.
Published in final edited form as: J Neurochem. 2009 Apr 4;109(5):1536–1543. doi: 10.1111/j.1471-4159.2009.06090.x

Table 1.

Dose-response parameters of L-KTP and D-KTP in wild-type and Pept2 null mice

L-KTP D-KTP
Wild-type Null Wild-type Null
ED50 (nmol) 20.8 ± 1.7 4.0 ± 0.4 10.3 ± 1.0 9.1 ± 0.8
N 1.7 ± 0.2 1.6 ± 0.2 2.0 ± 0.3 2.0 ± 0.3
Eo (% MPE) 26.5 ± 2.1 24.4 ± 3.3 25.7 ± 2.8 23.7 ± 2.7
r2 0.991 0.989 0.989 0.991

Dose-response parameters are expressed as estimate ± standard error (n=164 mice per genotype for L-KTP; n=100 mice per genotype for D-KTP). ED50 is the dose that causes 50% of the maximum effect due to dipeptide, N is the slope factor, Eo is the baseline effect in the absence of dipeptide, and r2is the coefficient of determination.