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. 2010 Jun 14;120(7):2508–2515. doi: 10.1172/JCI40040

Figure 2. PD-L1 expression on hematopoietic cells influences CTL function.

Figure 2

(A) IFN-γ and TNF-α production by GP33- and GP276-specific CD8+ T cells in the spleen 8 days after infection. Numbers in the upper quadrants represent the proportion of total CD8+ T cells expressing IFN-γ (left) or IFN-γ and TNF-α (right) after GP33 or GP276 stimulation. (B) The number of IFN-γ+ and (C) IFN-γ+TNF-α+ cells responding to NP396, GP33, GP276, GP118, and NP235 epitopes. n = 4–8 mice per group. Mean + SEM of data from 1 of 4 representative experiments are shown.