Figure 1. Myeloid cell profile in transplant rejection.
(A) Flow cytometric analysis of cell suspensions retrieved from native hearts and iso- and allografted hearts 7 days after transplantation. Lin, CD90/B220/CD49b/NK1.1/Ly-6G. Histograms on right depict the level of Ly-6C expression in respective populations. A representative experiment of 5 is shown. Tx, transplantation. (B) Time course of myeloid cell presence in heart and blood of allograft (black circles) and isograft (white circles) recipients. Animals receiving no transplants served as controls. (C) Ratio of Ly-6Chi vs. Ly-6Clo monocytes in the native heart, in isografts and allografts, and in blood. Data are shown as mean ± SEM; n = 3–5 per group.