Skip to main content
. 2010 Jun 23;120(7):2627–2634. doi: 10.1172/JCI42304

Figure 6. MPO-targeted MRI detects subtle transplant rejection.

Figure 6

(A) MR images acquired 2 hours after MPO-Gd in various groups and time points, H&E histology, and CD11b immunoreactive staining for myeloid cells and H&E histology. Scale bar: 25 μm. Arrows indicate enhancing regions after injection of MPO-Gd. (B) MR data acquired in mice treated with insufficient immunosuppression on day 7 after allograft. Pred, prednisolone. n = 4–6 per group. *P < 0.05 versus iso- and untreated allograft. (C) Serial imaging in isograft controls (n = 4) and single MHC class II mismatch (Bm12→B6, n = 7, *P < 0.05).