Table 2.
Alterations of MYC and TP53 copy numbers in early and advanced tubular adenocarcinomas of stomach
| Tumour depth | Mucosa | Submucosa | MP or deeper - | |||||
|---|---|---|---|---|---|---|---|---|
| Mucosal part | SM | Mucosal part | Deep | |||||
| cCGH (10) |
aCGH (13) |
cCGH (6) |
aCGH (3) |
aCGH (3) |
cCGH (9) |
aCGH (6) |
aCGH (6) |
|
| 8q(MYC)+ | 7 | 2 (2*) | 3 | 0 | 1 (1*) | 4 | 0 | 3 (2*) |
| 8q(MYC)- | 3 | 9 (9**) | 3 | 2 (2**) | 1 (1**) | 0 | 5 (5**) | 1 (0**) |
| 17p(TP53)+ | 3 | 10(9**) | 3 | 2 (2**) | 2 (1**) | 1 | 6 (5**) | 1 (0**) |
| 17p(TP53)- | 2 | 3 (2*) | 2 | 0 | 1 (1*) | 4 | 0 | 4 (2*) |
SM, the submucosa; MP, the muscularis propria. cCGH and aCGH, chromosome- and array-based comparative genomic hybridisation; Numerals in parentheses indicate the total number of the samples examined. Bold letters indicates the results of aCGH. Asterisks in parentheses indicate concomitance of MYC+ and TP53-. Double asterisks indicate concomitance of MYC- and TP53+.