Table 1.
Baseline comparison between patients treated with conventional and atypical APDs: demographic, outcome, pharmacological, and clinical variables.
| Conventional APD | Atypical APD | t | P | |||
|---|---|---|---|---|---|---|
| Mean | SD | Mean | SD | |||
| Age | 33.69 | 10.03 | 32.69 | 7.49 | 0.350 | 0.728 |
| Years of education | 9.15 | 3.33 | 10.73 | 2.76 | -1.56 | 0.126 |
| Age at onset | 22.76 | 5.44 | 26.03 | 7.60 | -1.37 | 0.176 |
| Years of illness | 10.92 | 8.83 | 6.65 | 5.98 | 1.78 | 0.082 |
| Number of prior episodes | 2.91 | 1.97 | 1.91 | 1.28 | 1.83 | 0.075 |
| Chlorpromazine equivalent units | 1116.15 | 708.97 | 602.88 | 264.60 | 3.29 | 0.002 |
| Biperiden (mg) | 1.08 | 1.98 | 0.30 | 0.78 | 1.75 | 0.087 |
| Diazepam units | 6.43 | 10.48 | 2.11 | 7.89 | 1.44 | 0.158 |
| Number of APD | 1.23 | 1.59 | 1.00 | 0.00 | 1.99 | 0.054 |
| PANSS positive | 17.84 | 4.89 | 10.15 | 2.98 | 6.093 | 0.0001 |
| PANSS negative | 19.69 | 9.12 | 21.11 | 8.82 | -0.470 | 0.641 |
| PANSS general | 31.61 | 8.69 | 30.11 | 7.07 | 0.578 | 0.567 |
| PANSS total | 69.15 | 17.36 | 61.38 | 16.32 | 1.37 | 0.178 |
| HRSD-21 | 4.87 | 3.56 | 6.12 | 4.97 | -0.65 | 0.519 |
| Premorbid adjustment | 4.50 | 1.06 | 3.60 | 2.14 | 0.113 | 0.265 |
APD: Antipsychotic Drug; SD: Standard Deviation; HRSD-21: Hamilton Rating Scale for Depression, 21 items