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Comparative analysis of melanoma initiation
| Tumor Cell Source | Frequency of Tumor Formation | ||
|---|---|---|---|
| CD271+ | CD271− | ||
| Patient samples | 70% (26/37) | 7% (3/41) | p = 0.04 |
| Xenografted samples (P0,Pi,Ps) |
74% (39/53) | 23% (10/43) | |
Comparison summary table of CD271+ and CD271− melanoma cells tumor engraftment frequencies isolated directly from clinical patient samples and from xenografted tumors. p value refers to CD271− population in patient vs. xenograft samples
