Table 6. Number of significantly detected viral variants throughout the study period for each patient.

Patient	Sample 1	Sample 2	Sample 3	Sample 4	Sample 5	Sample 6	Sample 7	Sample 8
1	57 a	17 b	38	33	17c	30	-	-
2	72	23	44	32	22	21	-	-
3	59	76	30	30	25	49	-	-
4	73	76	70	43	35	43	21	32
5	65	53	40	44	24	46	-	-
6	63	42	38	31	35	44	54	31

Footnotes

^aVariants in italic are sampled before any treatment is initiated.

^bVariants in bold are sampled during treatment failure.

^cVariants in normal text are sampled during treatment interruption.