Table V.
Results of haplotype transmission analysis in families with cleft lip with or without cleft palate by population.
| Marker Haplotype | Genes in Haplotype | Population | HBAT P-value2 |
|---|---|---|---|
| rs1928623-rs2251495-rs2808416 | Intergenic-MNAB (∼1Mb of STOM)- CRB2 | US | 0.02 |
| rs1888636-rs1418495-rs1335256-rs7859473 | PAPPA-intergenic-intergenic-CDK5RAP2 | US | 0.02 |
| rs7869023-rs913989 | ZNF79-SH2D3C | Spain | 0.03 |
| rs1928623-rs2251495-rs2808416-rs1928482 | Intergenic-MNAB (∼1Mb of STOM)- CRB2-KIAA1608 | Turkey | 0.02 |
| rs2014343-rs4979032 | Intergenic-GNG10 | Guatemala | 0.04 |
| rs357654-rs2236407-rs2297088 | PTCH-PTCH-PTCH | Guatemala | 0.03 |
| rs357654-rs2236407-rs2297088-rs10512248 | PTCH-PTCH-PTCH-PTCH | Guatemala | 0.02 |
| rs2300934-rs306796 | C5-STOM | Guatemala | 0.03 |
| rs306796-rs10739600 | STOM-TTLL11 (∼500kb of STOM) | Guatemala | 0.03 |
| rs306796-rs10739600-rs7853089-rs1928623 | STOM-TTLL11 (∼500kb of STOM)-C9orf18 (∼800kb of STOM) | Guatemala | 0.02 |
| rs2300934-rs306796 | C5-STOM | China | 0.04 |
| rs306796-rs10739600-rs7853089-rs1928623 | STOM-TTLL11 (∼500kb of STOM)-C9orf18 (∼800kb of STOM) | China | 0.04 |
Comprises analyses of US, Spain, and Turkey families pooled together.
Transmission distortion significant when p<0.05.