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. Author manuscript; available in PMC: 2011 Sep 1.
Published in final edited form as: J Neurosurg. 2010 Sep;113(3):598–608. doi: 10.3171/2009.9.JNS09844

Fig. 2.

Fig. 2

Effect of EPO on spatial learning function 31–35 days after TBI. TBI significantly impaired spatial learning at Days 32–35 compared to sham controls (p < 0.05). Delayed treatment with EPO (EPOx1 and EPOx3) improves spatial learning performance measured by a recent version of the water maze test at Days 33–35 compared with the saline group (p < 0.05). However, the spatial learning performance at Days 34 and 35 in the EPOx3 group is better than that in the EPOx1 group (p < 0.05). Data represent mean ± SD. *p < 0.05 vs. Saline group. #p < 0.05 vs. sham controls or EPOx3 group. N (rats/group) = 6 (Sham); 6 (Saline); 6 (EPOx1); 7 (EPOx3).