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. Author manuscript; available in PMC: 2011 Sep 1.
Published in final edited form as: J Neurosurg. 2010 Sep;113(3):598–608. doi: 10.3171/2009.9.JNS09844

Fig. 8.

Fig. 8

Effect of EPO on BrdU-positive cells in the injured cortex and ipsilateral DG 35 days after TBI. The cells with BrdU (brown stained) that clearlylocalized to the nucleus (hematoxylin stained) were counted as BrdU-positive cells (arrows in e and j). TBI alone (b, g) significantly increased the number of BrdU-positive cells in the ipsilateral cortex and DG compared to sham controls (p < 0.05). EPO treatment (EPOx1 and EPOx3) significantly increased the number of BrdU-positive cells in these regions (c, d, h, and i) compared to saline groups (p < 0.05). The number of BrdU-positive cells is shown in (k). Data represent mean ± SD. Scale bar = 50μm (a); 25μm (e). *p < 0.05 vs. Sham. #p < 0.05 vs. the saline group. N (rats/group) = 6 (Sham); 6 (Saline); 6 (EPOx1); 7 (EPOx3).