Table 2.

Published mRNA targets of the miR-17–92 cluster members

Target Gene Symbol	MicroRNA	Refs
APP	miR-106a	Patel et al. (2008)
BCL2L11 (Bim)	miR-17	Cloonan et al. (2008)
CCND1	miR-17, miR-20a	Yu et al. (2008)
CDKN1A (p21)	miR-106a, miR-106b, miR-17	Cloonan et al. (2008), Li et al. (2009), Ivanovska et al. (2008)
CDKN1C (p57)	miR-92b	Sengupta et al. (2009)
CTGF	miR-18a	Cloonan et al. (2008), Ohgawara et al. (2009)
E2F1	miR-106b, miR-20a	Petrocca et al. (2008a, b), O’Donnell et al. (2005), Pickering et al. (2009)
GAB1	miR-17	Cloonan et al. (2008)
HIF-1α	miR-17-92	Taguchi et al. (2008)
HIPK3	miR-92a	Landais et al. (2007)
IRF1	miR-17	Cloonan et al. (2008)
ITCH	miR-106b	Sampath et al. (2009)
MAPK9	miR-17	Cloonan et al. (2008)
MAPK14	miR-17, miR-20a, miR-106b	Carraro et al. (2009)
MYLIP	miR-92a	Landais et al. (2007)
NCOA3	miR-17	Cloonan et al. (2008), Hossain et al. (2006)
NR4A3	miR-17	Cloonan et al. (2008)
p63	miR-92	Manni et al. (2009)
PCAF	miR-17, miR-20a	Cloonan et al. (2008)
PKD1, PKD2	miR-17	Cloonan et al. (2008)
PPARA-C	miR-17	Cloonan et al. (2008)
PTEN	miR-19a	Cloonan et al. (2008), Lewis et al. (2003)
RB1	miR-106a	Volinia et al. (2006), Cloonan et al. (2008)
RB2/p130	miR-17-92	Wang et al. (2008)
RUNX1	miR-106a, miR-17, miR-20a	Fontana et al. (2007), Cloonan et al. (2008), Yu et al. (2008)
SOCS-1	miR-19a, miR-19b	Pichiorri et al. (2008)
STAT3	miR-17, miR-20a, miR-106b	Carraro et al. (2009)
TGFBR2	miR-17, miR-20a	Cloonan et al. (2008), Volinia et al. (2006)
THBS1	miR-19a	Cloonan et al. (2008)
TSG101	miR-17	Cloonan et al. (2008)
VEGFA	miR-106a, miR-106b, miR-17, miR-20a	Ye et al. (2008)