. 2010 May 12;57(8):767–773. doi: 10.1007/s12630-010-9325-1

Table 2.

Hemodynamic variables

	Baseline	Washout 2	Time after reperfusion (min)
			3	15	30	60
Heart rate (min⁻¹)
Control	366 ± 37	359 ± 35	365 ± 29	378 ± 5	372 ± 15	373 ± 14
IPC	367 ± 11	360 ± 23	365 ± 22	377 ± 2	365 ± 20	361 ± 24
IPC + Pax	357 ± 31	355 ± 32	276 ± 73	323 ± 47	324 ± 47	357 ± 20
MPC	367 ± 30	349 ± 28	383 ± 28	383 ± 28	383 ± 28	382 ± 30
MPC + Pax	346 ± 28	333 ± 34	248 ± 215	283 ± 142	375 ± 24	372 ± 17
Pax	336 ± 25	280 ± 29*	236 ± 126	342 ± 71	343 ± 69	344 ± 68
LVEDP (mmHg)
Control	12 ± 32	12 ± 5	53 ± 22^†	35 ± 15^†	26 ± 10	19 ± 7
IPC	11 ± 1	4 ± 4	52 ± 22^†	24 ± 13	19 ± 8	18 ± 7
IPC + Pax	14 ± 2	11 ± 11	62 ± 22^†	56 ± 32^†	45 ± 33^†	28 ± 18
MPC	12 ± 3	15 ± 5	51 ± 6^†	36 ± 7^†	29 ± 6	24 ± 7
MPC + Pax	13 ± 2	12 ± 4	57 ± 23^†	43 ± 24^†	38 ± 31	34 ± 34
Pax	11 ± 5	8 ± 4	43 ± 17^†	23 ± 10	21 ± 8	20 ± 9
dP/dt _max (mmHg · sec ⁻¹ 1,000)
Control	3.3 ± 0.6	3.3 ± 0.6	0.7 ± 0.9^†	0.6 ± 0.8^†	0.6 ± 0.7^†	0.4 ± 0.5^†
IPC	3.4 ± 1.1	3.5 ± 1.1	0.7 ± 1.0^†	1.4 ± 0.7^†	1.6 ± 0.5*,^†	1.5 ± 0.6*,^†
IPC + Pax	3.3 ± 0.4	2.7 ± 0.2	0.1 ± 0.1^†	0.3 ± 0.2^†	0.2 ± 0.1^†	0.1 ± 0.1^†
MPC	3.0 ± 0.4	2.7 ± 0.6	0.8 ± 0.4^†	1.0 ± 0.4^†	1.0 ± 0.3^†	1.0 ± 0.1*,^†
MPC + Pax	2.6 ± 0.5	2.5 ± 0.5	0.1 ± 0.1^†	0.3 ± 0.2^†	0.4 ± 0.3^†	0.3 ± 0.2^†
Pax	3.5 ± 1.1	3.0 ± 1.4	0.2 ± 0.1^†	0.4 ± 0.3^†	0.5 ± 0.4^†	0.5 ± 0.3^†
CF (mL · min ⁻¹ )
Control	16 ± 3	15 ± 2	9 ± 6^†	7 ± 6^†	7 ± 5^†	7 ± 6^†
IPC	14 ± 2	11 ± 5	7 ± 4^†	11 ± 6	8 ± 6	9 ± 6
IPC + Pax	13 ± 1	12 ± 2	11 ± 2	5 ± 2^†	4 ± 2^†	4 ± 4^†
MPC	16 ± 4	15 ± 4	9 ± 5^†	6 ± 3^†	5 ± 2^†	4 ± 2^†
MPC + Pax	15 ± 2	14 ± 2	13 ± 4	8 ± 3^†	7 ± 4^†	6 ± 4^†
Pax	14 ± 1	10 ± 2*,^†	4 ± 2^†	4 ± 2^†	3 ± 1^†	2 ± 1^†

Data are mean ± SD

IPC = ischemic preconditioning; MPC = morphine preconditioning; Pax = paxilline

LVEDP = left ventricular end-diastolic pressure; dP/dt_max = rate of left ventricular pressure development; CF = coronary flow; * P < 0.05 vs Control; ^† P < 0.05 vs Baseline