Fig. 4.

Effect of changes in relative diffusivity in lower CEP on glucose concentration profiles (darker areas at the center indicate critical regions). On the left are mid-sagittal views of solute profile (y = 0) and on the right are the superior translucent views of the entire disc showing the glucose extreme regions in grey. a Reference case with 100% CEPs permeability, b reduced lower CEP exchange area at 25% of the reference case, c reduced lower CEP exchange area at 5% of the reference case. Glucose extreme values are given in (nmol/mm³)