Table 5.
Gender: summary of studies reporting analysis of gender as a prognostic factor
| Author (reference) | Quality | Year | Patients | Gender | n | Outcome studied | Result | Comment |
|---|---|---|---|---|---|---|---|---|
| Huddart [24] | A | 1993 | 27 | M | 17 | 5-year OS (%) | 34 (↓) | p < 0.01 |
| F | 10 | 100 (↑) | ||||||
| Minehan [49] | A | 1995 | 79 | M | 47 | Survival | No effect | |
| F | 32 | |||||||
| Innocenzi [27] | B | 1997 | 65 | M | 45 | 5-year OS (%) | 60 | Not significant |
| F | 20 | 55 | ||||||
| Jyothirmayi [30] | A | 1997 | 23 | M | 12 | 5-year PFS/OS (%) | 65/52 (↓) | PFS p = 0.03 |
| F | 11 | 90/58 (↑) | OS p = 0.6, not significant | |||||
| Bouffet [5] (p) | A | 1998 | 73 | M | 37 | 10-year OS (%) | 79 (↑) | p = 0.04 |
| F | 36 | 39 (↓) | ||||||
| Rodrigues [60] | A | 2000 | 52 | M | 32 | 5-year PFS/CSS (%) | No effect | |
| F | 20 | |||||||
| Kim [34] | A | 2001 | 28 | M | 19 | Mean/median survival (months) | 73.5/12 | p = 0.940, not significant |
| F | 9 | 91.8/102 | ||||||
| Lee [41] | A | 2003 | 25 | M | 13 | 5-year LC/PFS/OS | No effect | |
| F | 12 | |||||||
| Santi [65] (m) | B | 2003 | 36 | M | 23 | Median survival (months) | 9 | p = 0.410, not significant |
| F | 13 | 11 | ||||||
| Robinson [59] | A | 2005 | 14 | M | 7 | 5-, 10-, 20-year OS, PFS | No effect | |
| F | 7 | |||||||
| Abdel-Wahab [2] | A | 2006 | 57 | M | 24 | 15-year OS/PFS | No effect | |
| F | 33 |
M male patients, F female patients, p: series of pediatric patients, m: series of high-grade tumors, ↑ positive influence on outcome measure, ↓ negative influence on outcome measure