Table 1.
Summary data of disc cell cluster prevalence, proportion of cells found in cell clusters and stress protein staining in the annulus fibrosus of control and pathological groups
| Annulus fibrosus | Age Mean ± SD (range) |
Percentage of disc sections with cell clusters | Percentage of total cells counted found in clusters | Percentage of positive cells [median (range)] Absolute no. of cells counted in “n” specimens |
||
|---|---|---|---|---|---|---|
| HSF-1 | HSP27 | HSP72 | ||||
| Control n = 12 |
62 ± 18 (22–90) |
58 | 2 | 10 (0–51) 2,400, n = 12 |
54 (20–82) 2,400, n = 12 |
46 (28–88) 2,300, n = 12 |
| DDD n = 14 |
46 ± 10† (33–60) |
36 | 2 | 2 (0–29) 2,660, n = 14 |
43 (3–79) 2,390, n = 14 |
29† (1–75) 2,560, n = 13 |
| Herniated n = 21 |
43 ± 13† (21–81) |
86 | 12 | 9 (0–70) 3,051, n = 17 |
52 (8–80) 3,608, n = 19 |
42 (5–90) 3,382, n = 19 |
| Protruded n = 11 |
41 ± 16† (21–81) |
73 | 5 | 9 (0–23) 1,280, n = 7 |
52 (8–80) 1,646, n = 9 |
37 (5–90) 1,547, n = 9 |
| Extruded n = 6 |
45 ± 11† (32–59) |
100 | 13 | 14 (1–34) 1,050, n = 6 |
59 (35–78) 1,202, n = 6 |
46 (20–72) 1,050, n = 6 |
| Sequestrated n = 4 |
45 ± 9 (36–58) |
100 | 24 | 16 (1–70) 721, n = 4 |
44 (38–58) 760, n = 4 |
52 (17–69) 785, n = 4 |
†A statistically significant difference (P < 0.05) between pathological and control groups