Table 2.
Gene title | Fold change | P value | Structure and function | Unigene |
---|---|---|---|---|
Muscle contraction and cytoskeleton genes | ||||
myosin heavy chain IIb | -1.51 | 0.023 | striated muscle contraction, actin binding | Ssc.56948 |
α-actin | 7.52 | 0.007 | striated muscle contraction | Ssc.1901 |
filamin A, alpha (actin binding protein 280) | 1.83 | 0.009 | striated muscle contraction | Ssc.55452 |
filamin B, beta (actin binding protein 278) | 1.84 | 0.030 | striated muscle contraction | Ssc.6691 |
tubulin, beta 2B | 2.50 | 0.004 | microtubule subunit protein, bind to colchicine,vincristine | Ssc.55842 |
tubulin, beta 6 | 2.02 | 0.046 | microtubule subunit protein, bind to colchicine,vincristine | Ssc.58401 |
α-actinin | 2.22 | 0.030 | regulate the length of actin | Ssc.5941 |
integrin, beta 3 | 1.76 | 0.029 | cell adhesion, integrin-mediated signaling pathway, regulation of cell migration | Ssc.44 |
catenin (cadherin-associated protein), alpha 1 | 1.61 | 0.025 | bind to cadherin | Ssc.58861 |
myosin binding protein C, slow type isoform 3 | 2.28 | 0.006 | bind to myosin | Ssc.13955 |
myosin binding protein H | -2.84 | 0.035 | bind to myosin | Ssc.20879 |
Extracellular matrix genes | ||||
fibromodulin | 3.12 | 0.013 | protein binding | Ssc.56133 |
fibronectin | 2.51 | 0.011 | extracellular region | Ssc.16743 |
tenascin-X | 2.94 | 0.001 | signal transduction | Ssc.28161 |
tenascin-C | 2.66 | 0.001 | cell adhesion, signal transduction | Ssc.16209 |
ankyrin 1 isoform 5 | -1.51 | 0.006 | attach to cytoskeleton, membrane-associated protein | Ssc.21745 |
collagen, type I, alpha 1 | 3.10 | 0.008 | phosphate transport, cell adhesion | Ssc.46811 |
collagen, type V, alpha 1 | 2.54 | 0.016 | phosphate transport, cell adhesion | Ssc.54853 |
Metabolic enzyme genes | ||||
pyruvate dehydrogenase kinase, isozyme 3 | 1.9 | 0.012 | phosphorylate pyruvate dehydrogenase | Ssc.19740 |
heme oxygenase (decyclizing) 1 | 3.25 | 0.025 | heme oxidation | Ssc.115 |
phosphoglucomutase | -1.58 | 0.005 | phosphotransferases, carbohydrate metabolic process | Ssc.4307 |
fructose 1,6-bisphosphatase 2 | 2.12 | 0.022 | carbohydrate metabolic, gluconeogenesis | Ssc.5127 |
creatine kinase | 1.65 | 0.020 | transferring phosphorus-containing groups | Ssc.9914 |
phosphofructokinase, platelet, partial | 2.31 | 0.012 | 6-phosphofructokinase activity | Ssc.862 |
glutathione S-transferase omega | -1.55 | 0.029 | glutathione transferase activity | Ssc.183 |
ADP-ribosyltransferase 3 | -2.68 | 0.004 | protein amino acid ADP-ribosylation | Ssc.15864 |
AXL receptor tyrosine kinase | 2.29 | 0.010 | regulates tyrosine phosphorylation in cellular signal transduction | Ssc.6566 |
protein tyrosine phosphatase 4a2 | -2.01 | 0.014 | dephosphorylation in cellular signal transduction, cell growth control | Ssc.54932 |
Stress protein genes | ||||
heat shock protein 2 | 1.91 | 0.005 | response to stress | Ssc.7654 |
heat shock protein 20kDa | 2.15 | 0.032 | response to stress | Ssc.13823 |
Transport protein genes | ||||
solute carrier family 12 (potassium/chloride transporters), member 4 | 2.42 | 0.016 | ion transport | Ssc.4097 |
aquaporin 3 | -3.66 | 0.026 | water reabsorption | Ssc.3832 |
oculocutaneous albinism 2 | -12.6 | 0 | citrate transmembrane transport | Ssc.15775 |
Transcription factor genes | ||||
transforming growth factor, beta induced | 2.9 | 0.040 | binds to type I, II, IV, VI collagens and fibronectin | Ssc.16671 |
transforming growth factor, beta 3 | 1.99 | 0.027 | cell differentiation, embryogenesis and development | Ssc.27593 |
transforming growth factor, beta 1 | 1.85 | 0.003 | immune, regulation of cell proliferation and differentiation | Ssc.76 |
transcription factor GATA-6 | 2.23 | 0.040 | positive regulation of transcription | Ssc.2258 |
general transcription factor IIE, polypeptide 2, beta 34kDa | 1.69 | 0.003 | regulation of transcription initiation | Ssc.3369 |
homeobox protein A10 | 2.27 | 0.001 | regulation of transcription, DNA-dependent | Ssc.26254 |
myocyte enhancer factor 2C | 1.58 | 0.011 | regulation of transcription, DNA-dependent | Ssc.34788 |
four and a half LIM domains 1 protein, isoform C | 1.53 | 0.027 | metal ion binding | Ssc.14463 |
epidermal growth factor | -1.57 | 0.040 | calcium ion binding, integral to membrane | Ssc.87 |
Hormone genes | ||||
parathyroid hormone-like hormone | 1.77 | 0.003 | hormone activity | Ssc.9991 |
Others | ||||
calponin 1 | 1.67 | 0.015 | actomyosin structure organization and biogenesis, actin and calmodulin binding | Ssc.9013 |
calcyclin binding protein isoform 1 | -1.76 | 0.012 | ubiquitin-mediated degradation of beta-catenin | Ssc.10299 |
cathepsin B | 1.59 | 0.045 | proteolysis | Ssc.53773 |
cathepsin H | 1.83 | 0.018 | proteolysis | Ssc.3593 |
cathepsin Z | 1.65 | 0.016 | proteolysis | Ssc.16769 |
mitochondrial ribosomal protein S26 | -2.12 | 0.033 | catalytic function in reconstituting biologically active ribosomal subunits | Ssc.12554 |
p53 protein | 1.64 | 0.028 | control of cell proliferation | Ssc.16010 |
p55 TNF receptor superfamily, member 1A | 1.51 | 0.008 | cell surface receptor linked signal transduction | Ssc.4674 |
interleukin 15 | -1.59 | 0.031 | stimulating the proliferation of T-lymphocytes | Ssc.8833 |
cytochrome P450, family 27, subfamily A, polypeptide 1 | 1.73 | 0.012 | biosynthesis of steroids, fatty acids and bile acids | Ssc.3804 |
“+” and “-” indicated the up- and down- regulated expression in soleus group, respectively.