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Micro-PET scans showing the effect of TPZ and MnSOD-PL, plus C225, on CAL-33 orthotopic tumors in cheek of 14 Gy-irradiated nude mice. Mice were injected with FMISO before scanning. Mouse 1 is a nonirradiated control, mouse 2 was treated with TPZ (60 mg/kg) 10 min before 14 Gy, and mouse 3 with MnSOD-PL intraorally, C225, and TPZ before irradiation.
