Table 1.

Summary of neuronal and gial mediators of functional hyperemia.

Only cortical mediators identified in vivo are listed. Neuronal and glial metabolism by-products (e.g., CO₂, H⁺, adenosine…) are not included. NO, nitric oxide; VIP, vasoactive intestinal polypeptide; PgE₂, prostaglandin E₂; EETs, epoxyeicosatrienoic acids; NOS, nitric oxide synthase; NPY, neuropeptide Y; COX, cyclooxygenase, NMDA-R, N-methyl d aspartate receptors, iGluRs; ionotropic glutamate receptors, mGluR, metabotropic glutamate receptors; VSMC, vascular smooth muscle cell, sGC, soluble guanylate cyclase, VPAC1, VIP/PACAP receptor type 1; EP, prostaglandin E₂ receptors; GPCR, G protein coupled receptor. K_Ca, Ca²+-activated K⁺ channels; K_ir, inward rectifier K⁺ channels; g, conductance. References can be found in the main list.