Table 1.
Case | Age (years)/gender | Diagnosis | Neurological status pre-/post-op | Initial surgery | Revision surgery | Follow-up (months) |
---|---|---|---|---|---|---|
1 | 6/male | Hurler’s disease | Lower extremity weakness, sleep apnea, myelopathy/improvement | Laminectomy posterior in situ fusion occiput-C4 ICBG, halo-jacket | Repeat posterior ICBG C0–C4, rhBMP-2, halo-jacket | 18 |
2 | 2/male | Congenital cervical kyphosis | Lower extremity weakness/improvement, able to ambulate | Posterior in situ fusion C3–T4, ICBG, halo-jacket | Repeat posterior ICBG C3–T4, rhBMP-2, Minerva | 11 |
3 | 10/male | Thoraco-lumbar kyphosis HSAN 4 | Normal | Posterior instrumentation T11–L4, ICBG anterior decompression + cage T12–L3, | Repeat posterior ICBG, rhBMP-2, TLSO brace | 13 |
ICBG Iliac crest bone graft, HSAN hereditary sensory autonomic neuropathy