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Phase II data for nilotinib second-line to imatinib failure
| Disease | n |
% Response |
Overall survival | ||
|---|---|---|---|---|---|
| CHR |
Cytogenetic response |
||||
| Major | Complete | ||||
| CML Chronic | 321 | 77 | 57 | 41 | 91% (18 months) |
| CML Accelerated | 136 | 26 | 31 | 19 | 81% (12 months) |
| CML Blastic | 136 | 11 | 40 | 29 | 42% (12 months) |
Abbreviations: CHR, complete hematologic response; CML, chronic myeloid leukemia.
