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Similar spectra of ENU-induced mutations from forward and reverse genetic approaches in zebrafish. Mutations identified by TILLING (black bars) and in forward genetic screens (grey bars) are grouped into one of six possible classes of mutation. TILLING data are based on 982 mutations identified in the Moens lab. Forward screen data were mined from the primary literature for an arbitrary subset of zebrafish mutations that were identified through positional cloning.
