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Association between major principal components of the DNMTs and BPDE-induced chromatid breaks per cell
| Statistics | DNMT1 | DNMT3A | DNMT3B |
| Number of PCs | 2 | 8 | 2 |
| Cumulative variance explained (%) | 87.7 | 82.4 | 87.3 |
| P-value of LRTa | 0.028 | 0.092 | 0.033 |
PC, principal components.
Adjustment for sex, seeding count and current smoking status were included in the multiple linear regression model.
