. 2010 Jan 9;19(6):931–939. doi: 10.1007/s00586-009-1263-7

Table 2.

Radiographic and biomechanical analysis of rat intertransverse process spinal fusion

Parameters	S	A	AL	AB	ALB
Radiographic fusion score	0 ± 0	1 ± 0.1	1.3 ± 0.1	3.1 ± 0.2*	3.0 ± 0.1
Radiographic fusion score	0 ± 0	2.0 ± 0.1	2.0 ± 0	4.0 ± 0*	3.4 ± 0.2
Total fusion mass area (mm²)	0 ± 0	163 ± 10	190 ± 12	266 ± 15*	230 ± 11
Total fusion mass area (mm²)	0 ± 0	167 ± 14	192 ± 6.0	225 ± 17	297 ± 26 ⁺
Fusion mass in SROI (mm²)	4.2 ± 1.0	25.3 ± 3.0	29.0 ± 2.0	45.0 ± 3.0*	35.0 ± 3.0
Fusion mass in SROI (mm²)	4.3 ± 1.0	26.0 ± 5.0	30.0 ± 2.0	27.0 ± 4.0	45.0 ± 4.0 ⁺
Manual palpation for fusion (%)	0	50	75	100	80
Manual palpation for fusion (%)	0	70	33	100	71⁺
Range of motion (mm)	0.5 ± 0.2	0.2 ± 0.1	0.2 ± 0	1 ± 0	1 ± 0.1
Range of motion (mm)	0.3 ± 0.1	0.1 ± 0	0.5 ± 0.1**	0.1 ± 0	0.1 ± 0
Hysteresis (N mm)	0.6 ± 0.2	0.5 ± 0.2	1 ± 0.1	0.2 ± 0	1 ± 0.2
Hysteresis (N mm)	1.0 ± 0.2	0.5 ± 0.2	1.1 ± 0.3**	0.2 ± 0.1	1.0 ± 0.2

Mean ± SE (n = 28/group). Upper figures in columns = 21 days, lower figures = 44 days.

SROI square region of interest, S sham, A autograft, AL autograft + l-NAME, AB autograft = rhBMP-2, ALB autograft + rhBMP-2 + l-NAME

* AB/A, P < 0.001, ** AL/A, P < 0.05, ⁺ ALB/AB, P < 0.05