Table 2.
Group | Pre-arrest | Post-resuscitation phase | Friedmann | ||||
5 min | 30 min | 90 min | 240 min | ||||
Liver | TELM | 0.79 ± 0.14 | 0.63 ± 0.13* | 0.78 ± 0.14 | 0.75 ± 0.15 | 1.10 ± 0.10* | P < 0.05 |
(ml/min/g) | Control | 0.68 ± 0.2 | 0.46 ± 0.09* | 0.58 ± 0.09 | 0.81 ± 0.09 | 0.93 ± 0.20* | P < 0.01 |
Spleen | TELM | 3.45 ± 0.59 | 0.53 ± 0.15* | 3.45 ± 0.76 | 3.99 ± 0.67 | 3.49 ± 0.39 | P < 0.01 |
(ml/min/g) | Control | 3.60 ± 0.26 | 0.77 ± 0.37* | 4.44 ± 0.59 | 4.89 ± 0.41 | 3.82 ± 0.40 | P < 0.001 |
Stomach | TELM | 0.29 ± 0.06 | 0.08 ± 0.01* | 0.17 ± 0.02 | 0.23 ± 0.03 | 0.30 ± 0.04 | P < 0.001 |
(ml/min/g) | Control | 0.23 ± 0.03 | 0.06 ± 0.01* | 0.16 ± 0.02 | 0.20 ± 0.02 | 0.28 ± 0.04 | P < 0.0001 |
Pancreas | TELM | 0.26 ± 0.01 | 0.05 ± 0.01* | 0.18 ± 0.01 | 0.37 ± 0.04 | 0.55 ± 0.05* | P < 0.00001 |
(ml/min/g) | Control | 0.25 ± 0.04 | 0.05 ± 0.01* | 0.15 ± 0.02 | 0.31 ± 0.05 | 0.48 ± 0.05* | P < 0.00001 |
Jejunum | TELM | 0.37 ± 0.03 | 0.20 ± 0.02* | 0.36 ± 0.03 | 0.41 ± 0.04 | 0.55 ± 0.05* | P < 0.0001 |
(ml/min/g) | Control | 0.44 ± 0.02 | 0.23 ± 0.02* | 0.41 ± 0.04 | 0.42 ± 0.02 | 0.52 ± 0.04* | P < 0.001 |
Colon | TELM | 0.40 ± 0.03 | 0.20 ± 0.02* | 0.48 ± 0.04 | 0.51 ± 0.03 | 0.57 ± 0.03* | P < 0.00001 |
(ml/min/g) | Control | 0.49 ± 0.07 | 0.25 ± 0.04* | 0.61 ± 0.08 | 0.61 ± 0.07 | 0.57 ± 0.09* | P < 0.0001 |
Kidney | TELM | 3.40 ± 0.10 | 2.36 ± 0.41 | 2.67 ± 0.21 | 3.85 ± 0.30 | 4.62 ± 0.22* | P < 0.0001 |
(ml/min/g) | Control | 3.40 ± 0.21 | 2.50 ± 0.41 | 2.82 ± 0.11 | 3.80 ± 0.22 | 4.63 ± 0.16* | P < 0.001 |
Adrenal gland | TELM | 1.69 ± 0.20 | 6.36 ± 1.56* | 3.11 ± 0.81 | 2.01 ± 0.21 | 2.43 ± 0.35* | P < 0.05 |
(ml/min/g) | Control | 1.70 ± 0.09 | 5.09 ± 0.97* | 2.14 ± 0.16 | 2.51 ± 0.24 | 2.19 ± 0.22 | P < 0.05 |
TELM = angiotensin II antagonist telmisartan; *P < 0.05 vs pre-arrest values by Wilcoxon matched pairs test.