TABLE 2.
Causes of intubation, ventilatory parameters and gas-exchange abnormalities
| ZEEP=0 cmH2O (n=33) | PEEP=5 cmH2O (n=30) | P | |
|---|---|---|---|
| Reasons for intubation, n | |||
| Respiratory | 15 | 16 | 0.35 |
| Cardiovascular | 2 | 3 | 0.78 |
| Mixed cardiorespiratory | 5 | 4 | 0.40 |
| Neurological | 8 | 5 | 0.60 |
| Miscellaneous | 3 | 2 | 1.00 |
| Initial ventilatory parameters | VC (n=23)/PC (n=10) | VC (n=21)/PC (n=9) | |
| Vt, mL/kg EBW | 7.3 (6.4–8.4) | 8.3 (6.1–9.2) | 0.99 |
| mPaw, cmH2O | 10 (6.5–13) | 10 (9–12) | 0.59 |
| RR, breaths/min | 12 (11–17) | 12 (12–15) | 0.89 |
| Gas-exchange parameters before intubation | |||
| PaO2/FiO2 | 176 (74–414) | 250 (76–422) | 0.79 |
| pH | 7.37 (7.3–7.45) | 7.41 (7.3–7.44) | 0.77 |
| Gas-exchange parameters 90 min after MV initiation* | |||
| PaO2/FiO2 | 222.5 (187–274) | 269 (218–392) | 0.10 |
| pH | 7.39 (7.34–7.47) | 7.37 (7.3–7.43) | 0.37 |
Data presented as median (interquartile range) unless indicated otherwise.
*Four and three arterial gas measurements were missing in the zero end-expiratory pressure (ZEEP) and positive end-expiratory pressure (PEEP) groups, respectively. EBW Effective body weight; FiO2 Fraction of inspired oxygen; mPaw Mean airway pressure; MV Mechanical ventilation; PaO2 Partial pressure of oxygen; PC Pressure-controlled MV; RR Respiratory rate; VC Volume-controlled MV, Vt Tidal volume