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. Author manuscript; available in PMC: 2010 Jul 8.
Published in final edited form as: Pharm Res. 2009 Sep 11;26(11):2513–2522. doi: 10.1007/s11095-009-9967-2

Fig. 5.

Fig. 5

Transepidermal water loss (TEWL), as measured using a Delfin VapoMeter® (Delfin Technologies Ltd, Kuopio, Finland) by application of the device for 15 s to nonmicroorganism-loaded porcine skin immediately following removal of an inserted hypodermic needle (a), immediately following removal of a microneedle array that was left in place for 24 h following puncture (b) and immediately following removal of a microneedle array that was removed immediately following puncture (c).