Fig. 3.

nav RBs exhibit decreased voltage-gated sodium currents, but retain the ability to generate overshooting action potentials. (A) Whole-cell current responses recorded in wild type and nav mutant RBs (48-52 hpf) following membrane depolarizations. (B) Peak inward current plotted as a function of the membrane potential. Values represent the average ± SEM (n = 12 for wild type, and n = 12 for mutant). * denotes that difference between wild type and mutant was significant (t- test, p < 0.05). (C) Action potentials in wild type and nav RBs evoked by depolarizing current injections (2 ms) shown below.