Fig. 1.

Cryo-EM density map and backbone models of GCRV. (a) Density map of an asymmetric unit (left panel) segmented out from the GCRV virion reconstruction (upper right). The trimers (Q, R, S, T) are labeled using the nomenclature of bluetongue virus and are colored differently.¹⁸ (b) Density map of an asymmetric unit of the core (left). The core map (upper right) was computationally extracted from the GCRV virion map shown in (a). (c) Cryo-EM densities (wire frames) and models (ribbons) of α-helices (left and middle) and a β-sheet (right) selected from VP6A and VP3A. Densities corresponding to some bulky side chains and partially resolved β-strands are resolved. (d) Backbone models of the virion (left) and an asymmetric unit (right). (e) Backbone models of the core (left) and an asymmetric unit (right). Different proteins (VP1, VP3A, VP3B, VP6A, VP6B and VP1) are shown in different colors.