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Alignment of AcCa1 and AcCa2 sequences with homologs from Arabidopsis and prokaryotes. Acanthamoeba AcCa1 and AcCa2 are aligned with Arabidopsis CA1 and CAL1 along with an α-proteobacterial (Ehrlichia canis) γCA homolog and archaeal Cam (Methanosarcina thermophila). Critical amino acids described in text are referred to according to the Cam nomenclature. H42 and C137 of CA1 are denoted by * and %, respectively. Shading of columns reflects amino acid similarity of ≥ 80%.
