Table 1. HSV1 proteins potentially interacting with cytosolic host factors.
| HSV1 - structural protein | Copies/Virion | MW [kDa] | Method of Analysis * |
| Capsid protein | |||
| VP5 (UL19) - hexon+penton | 955 | 149 | IB, MS |
| VP26 (UL35) - hexon surface | 900 | 12 | K/O, IB, MS |
| VP19c (UL38) - triplex | 320 | 50 | IB, MS |
| VP23 (UL18) - triplex | 640 | 34 | MS |
| VP24 (pUL26-N-term) | 150 | 27 | MS |
| Minor capsid-associated protein - required for DNA packaging | |||
| pUL6 - portal | 12 | 74 | IB |
| pUL17 | 40 | 75 | IB, MS |
| pUL25 | 82 | 63 | IB, MS, IEM |
| Inner tegument protein | |||
| pUS3 - protein kinase | ? | 53 | K/O, IB, IEM |
| pUL36 - deubiquitinase | 110–150 | 336 | IB, MS, IEM |
| pUL37 (GFPUL37) | 30–40 | 121 | IB, MS, IEM |
| Tegument protein with enzymatic activity | |||
| pUL13 - protein kinase | ? | 57 | - |
| pUL23 - thymidine kinase | ? | 41 | - |
| pUL39 - ribonucleotide reductase subunit | ? | 124 | - |
| pUL40 - ribonucleotide reductase subunit | ? | 38 | - |
| vhs (virus host shut off protein, UL41) | ? | 55 | IB |
| pUL50 - dUTPase | ? | 39 | - |
| Other tegument protein | |||
| ICP0 (RL2) | ? | 79 | IB |
| ICP4 (RS1) | ? | 133 | IB |
| ICP34.5 (RL1) | ? | 26 | IB |
| pUL7 | ? | 33 | - |
| pUL11 - myristylated | ? | 11 | IB |
| pUL14 | 20–40 | 24 | IB |
| pUL16 | ? | 40 | IB, MS |
| pUL21 | ? | 58 | MS |
| pUL51 | ? | 26 | - |
| pUL55 | ? | 21 | - |
| pUS2 - prenylated | ? | 33 | - |
| pUS10 | ? | 34 | - |
| Major tegument protein | |||
| VP11/12 (UL46) | 410–1700 | 78 | K/O, MS |
| VP13/14 (UL47) | 1800 | 74 | IB, MS, IEM |
| VP16 (UL48; αTIF) | 1000–2000 | 54 | IB, MS, IEM |
| VP22 (UL49) | 1000–1500 | 32 | IB, MS, IEM |
| pUS11 – binds RNA & ribosomes | 600–1000 | 18 | K/O, IB |