Figure 2. Total lymphocyte deficiency reduced AngII-induced atherosclerosis in male mice.

The percent area of grossly discernable atherosclerotic lesions was measured in the arch and thoracic regions of aortas recovered from apoE −/− mice that are either Rag-1 +/− or −/− in male (A) and female groups (B). The area for each individual mouse is represented by circle or inverted triangle; diamonds represent means and bars represent SEMs. Statistical analyses were performed by Kruskal Wallis with follow up Z test.