Table 1.
Uncoated | Chitosan-Coated | ||||
---|---|---|---|---|---|
Duration of Implant (Days) | Vehicle | TGF-β1 | Vehicle | TGF-β1 | |
DNA Content (g) | 1 | 0.439 (0.4388-0.439) | 0.439 (0.439–0.4394) | 0.425 (0.413–0.436) | 0.418 (0.406–0.429) |
3 | 0.483 (0.446–0.520) | 0.456 (0.421–0.490) | 0.638* (0.443–0.832) | 0.582** (0.387–0.776) | |
5 | 0.519 (0.484–0.554) | 0.464 (0.429–0.500) | 0.470 (0.363–0.576) | 0.512 (0.412–0.611) | |
7 | 0.525 (0.473–0.577) | 0.511 (0.455–0.566) | 0.399 (0.390–0.408) | 0.397 (0.389–0.404) |
The data are presented as means with 95% confidence intervals. The group marked (*) has significantly higher DNA content than all other groups in the table except the group marked with (**). The highest p-value occurring between this group and the uncoated, day 7 vehicle injected group at p=0.029. All other p-values when compared to this marked (*) value are below this p-value. The group marked (**) had significantly higher values of DNA content than all groups in the table with the exception of vehicle and TGF-β1 injected, day 7 uncoated scaffolds and vehicle injected day 5 and day 3 uncoated scaffolds. The highest p-value amongst the groups significantly different from (**) occurred between this group and TGF-β1 injected, day 5 uncoated scaffolds with p=0.0228. All other p-values when compared to this marked (**) value are below this p-value. These p values are based on the results of post-hoc testing using Student’s t-test (n=7 or 8).