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. Author manuscript; available in PMC: 2011 Aug 15.
Published in final edited form as: Biochem Pharmacol. 2010 May 6;80(4):448–454. doi: 10.1016/j.bcp.2010.04.030

Figure 4.

Figure 4

cDDP accumulation and cytotoxicity. A, Net accumulation of Pt in MEF cells following 5 min exposure to 30 µM cDDP. B, Inhibition of growth of MEF cells following 5 minute exposure to varying concentrations of cDDP. (●), CTR1−/−; (□), myc-CTR1−/−/wt; (▲), myc-CTR1−/−/M2; (▼), myc-CTR1−/−/Truncated. All values represent means of 6 independent experiments each containing triplicate cultures. Vertical lines, ± SEM.