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. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: J Stroke Cerebrovasc Dis. 2010 May 14;19(4):261–268. doi: 10.1016/j.jstrokecerebrovasdis.2009.05.001

Table 2B.

Moderating effect of apoE4 status on the relationship between stroke risk and brain volume

Overall (beta±se) P-value for interaction with apoE4 With no apoE4 (2/2, 2/3, 3/3) (beta±se) apoE4 present (3/4, 4/4) (beta±se)
Total brain volume -0.338±0.057*** ns -0.353 ± 0.064*** -0.276 ± 0.132*
White matter hyperintensities 0.208 ± 0.060*** ns 0.200 ± 0.069** 0.222 ± 0.126
Frontal Lobe volume -0.198 ± 0.060*** ns -0.188 ± 0.068** -0.233 ± 0.127
Temporal Lobe volume -0.193 ± 0.066** ns -0.174 ± 0.075* -0.240 ± 0.138
Temporal horn volume 0.155 ± 0.062* Ns 0.120 ± 0.070 0.270 ± 0.135*
Lateral ventricular volume 0.205 ± 0.060*** 0.012 0.124 ± 0.068 0.490 ± 0.124***
Hippocampal volume -0.159 ± 0.094 ns -0.141 ± 0.102 -0.195 ± 0.227