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. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: J Stroke Cerebrovasc Dis. 2010 May 14;19(4):261–268. doi: 10.1016/j.jstrokecerebrovasdis.2009.05.001

Table 3B.

Moderating effect of apoE4 status on the relationship between systolic blood pressure and brain volume

Overall (beta±se) P-value for interaction with apoE4 apoE4 absent (2/2, 2/3, 3/3) (beta±se) apoE4 present (3/4, 4/4) (beta±se)
Total brain volume -0.040 ± 0.020* ns -0.047 ± 0.022* -0.013 ± 0.044
White matter hyperintensities 0.022 ± 0.021 ns 0.031 ± 0.024 -0.006 ± 0.042
Frontal Lobe volume -0.042 ± 0.020* ns -0.049 ± 0.023* -0.017 ± 0.042
Temporal Lobe volume -0.011 ± 0.023 ns -0.009 ± 0.026 -0.011 ± 0.045
Temporal horn volume 0.054 ± 0.022* ns 0.052 ± 0.025* 0.059 ± 0.045
Lateral ventricular volume 0.060 ± 0.021** ns 0.052 ± 0.024* 0.082 ± 0.042*
Hippocampal volume 0.024 ± 0.033 ns 0.024 ± 0.037 0.036 ± 0.075