Skip to main content

View full-text article in PMC

. Author manuscript; available in PMC: 2011 Jul 1.

Published in final edited form as: J Stroke Cerebrovasc Dis. 2010 May 14;19(4):261–268. doi: 10.1016/j.jstrokecerebrovasdis.2009.05.001

Table 4B.

Moderating effect of apoE4 status on the relationship between Diabetes diagnosis and brain volume

	Overall (beta±se)	P-value for interaction with apoE4	apoE4 absent (2/2, 2/3, 3/3) (beta±se)	apoE4 present (3/4, 4/4) (beta±se)
Total brain volume	-0.335 ± 0.058^***	ns	-0.354 ± 0.065^***	-0.288 ± 0.128^*
White matter hyperintensities	0.049 ± 0.061	0.061	-0.013 ± 0.070	0.258 ± 0.123^*
Frontal Lobe volume	-0.354 ± 0.060^***	ns	-0.388 ± 0.068^***	-0.256 ± 0.124^*
Temporal Lobe volume	-0.061 ± 0.066	ns	-0.077 ± 0.076	-0.037 ± 0.135
Temporal horn volume	0.186 ± 0.063^**	ns	0.172 ± 0.072^**	0.233 ± 0.133
Lateral ventricular volume	0.197 ± 0.062^**	ns	0.211 ± 0.072^**	0.165 ± 0.123
Hippocampal volume	-0.178 ±0.104	ns	-0.182 ± 0.116	-0.253 ± 0.238

^*

p<0.05

^**

p<0.01

^***

p<0.001