Table 3.
Cardiac function in control mice and mice given repetitive injections of iron dextran for a total of 4 weeks. Values shown are mean ± 1 standard deviation (n = 10 in each group). In all measures except for heart rate, iron treated mice differ from controls at p<0.001 (Student’s t test, two-tailed).
Group | Heart Rate | AWTd | PWTd | RWT | LVIDD | LVEF single plane |
---|---|---|---|---|---|---|
Control | 512±36.36 | 0.70±0.06 | 0.83±0.07 | 0.43±0.14 | 3.6±0.26 | 0.68±0.06 |
Iron treated | 472±29.79 | 0.99±0.15 | 0.93±0.01 | 0.67±0.05 | 2.9±0.37 | 0.80±0.07 |
Abbreviations: AWTd: anterior wall thickness in diastole. PWTd: posterior wall thickness in diastole. RWT: relative wall thickness = (AWT + PWT)/LVIDD. LVIDD: left ventricle internal diameter in diastole. LVEF: left ventricular ejection fraction = (EDV - ESV)/ED.