Skip to main content
. Author manuscript; available in PMC: 2011 Aug 1.
Published in final edited form as: Exp Mol Pathol. 2010 Apr 28;89(1):1–8. doi: 10.1016/j.yexmp.2010.04.001

Fig 6.

Fig 6

Study of the formation of MDBs in Hepa 1–6 cells treated continuously for 43 days with a cotreatment of IFNg and TNFa. UbD localized with aggresomes (white arrows) similar to the MDB-like aggresomes seen after 21 days of cotreatment with cytokines. The immunostaining was done using antibodies against endogenous UbD (green) and ubiquitin (red). Nuclei were stained with DAPI (blue). A to F; cells stained with UbD antibody. G to L; cells stained with Ubiquitin antibody. M to R; cells stained with DAPI (Magnification ×175).