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. Author manuscript; available in PMC: 2011 Aug 1.
Published in final edited form as: Exp Mol Pathol. 2010 Apr 28;89(1):1–8. doi: 10.1016/j.yexmp.2010.04.001

Fig 7.

Fig 7

Study of the formation of MDBs in Hepa 1–6 cells treated continuously for 43 days with a cotreatment of IFNg and TNFa. CK8 localized with aggresomes (white arrows) similar to MDB-like aggresomes, after 21 days of cotreatment with cytokines. The immunostaining is done with antibodies against endogenous CK8 (green), ubiquitin (red). The nuclear stain was DAPI (blue). A to C cells stained with CK8 antibody. D to F cells stained with Ubiquitin antibody. G to I cells stained with DAPI (Magnification ×175).