Table 5.
Logistic Regression Analysis for Association of Genotype with Neurodevelopmental Delay at Age 2 Years*
Gene | Polymorphism | RS Number | OR (95% CI)† | Best Model |
---|---|---|---|---|
IL1-β | −511A/G | 16944 | 3.1 (1.2–8.2) | Recessive |
IL4-R | Ile50Val, 148 (A/G) | 1805010 | 0.6 (0.4–0.9) | Additive |
IL6 | −176G/C | 2234683 | 2.2 (1.2–3.9) | Dominant |
IL6 | −174G/C | 1800795 | 0.5 (0.2–1.2) | Dominant |
Covariates included gestational age at delivery, small for gestational age (SGA) status, gender, steroid treatment group, race, smoking, and maternal level of education.
OR, odds ratio; CI, confidence interval.