Table 3.
Risk of squamous cell carcinoma stratified by β human papillomavirus seropositivity
| Risk factor | Seronegative (No case/control) | Seropositive (No case/control) | Strata specific odds ratio (95% CI)* |
|---|---|---|---|
| Skin sensitivity†: | |||
| Tan without sunburn | 32/77 | 36/77 | 1.19 (0.66 to 2.14) |
| Mild sunburn with some tanning | 141/219 | 154/189 | 1.22 (0.90 to 1.65) |
| Painful sunburn with peeling | 111/114 | 120/84 | 1.46 (0.99 to 2.15) |
| Severe sunburn with blistering | 26/24 | 40/19 | 1.85 (0.84 to 4.07) |
| Skin sensitivity: | |||
| Tan without sunburn/mild sunburn with some tanning | 173/296 | 190/266 | 1.19 (0.91 to 1.56) |
| Painful sunburn with peeling/severe sunburn with blistering | 137/138 | 160/103 | 1.54 (1.09 to 2.18) |
| No of lifetime painful sunburns: | |||
| None | 82/142 | 87/114 | 1.31 (0.88 to 1.95) |
| 1-2 | 61/127 | 78/104 | 1.45 (0.95 to 2.24) |
| 3-9 | 43/62 | 48/52 | 1.32 (0.75 to 2.29) |
| ≥10 | 121/100 | 132/95 | 1.17 (0.80 to 1.71) |
| Oral glucocorticoids: | |||
| No | 272/400 | 295/336 | 1.23 (0.97 to 1.55) |
| Yes | 23/25 | 36/18 | 3.21 (1.22 to 8.44) |
*Stratum specific odds ratio for β human papillomavirus positivity; adjusted for age and sex for skin sensitivity and number of lifetime painful sunburns; additionally adjusted for level of education, cigarette smoking status at one year before the reference date, skin sensitivity, and number of lifetime painful sunburns for oral glucocorticoids.
†Defined as reaction to one hour of sun exposure first time in summer.