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. 2010 May 19;4(2):475–493. doi: 10.1007/s12072-010-9183-5

Table 1.

Diagnostic criteria for AIH

Parameters Diagnosis of autoimmune hepatitis
Clinical Female gender
Associated with other autoimmune diseases
Autoantibodies ANA or SMA >1:40 (type 1)
LKM >1:40 (type 2)
SLA+ (type 3)
Immunoglobulin IgG > upper normal limit
Biochemistry Hepatitic picture (raised AST/ALT levels)
Histology Plasma cell-rich mononuclear infiltrate
Interface hepatitis with ballooning and rosetting of periportal hepatocyte; +/− periportal fibrosis
Lobular necroinflammatory activity
No bile duct loss or chronic cholestasis
Radiology and ERCP Normal
Exclusion of other etiology Exclude viral hepatitis, metabolic, drug, and alcoholic etiology
Response to steroid Good