Fig. 3.

TL1A enhancement of IL-12/IL-18-induced cytotoxicity to Daudi cells is mediated mainly by NK cells. a, b Purified NK (a) and the non-NK fraction (b) from the same donor were cultured, and their cytolytic activity was tested against Daudi in a ⁵¹Cr-release assay. c, d IFN-γ production by purified NK (c) and non-NK cells (d) from four different donors was measured with and without TL1A. Mean values and SEM of two experiments are shown for the lytic activity. Individual donor results for IFN-γ production and the fold increase for each donor are shown. The average fold increase for the four donors is displayed on the side of each figure