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. 2010 Jun 14;107(26):11847–11852. doi: 10.1073/pnas.1007158107

Fig. 1.

Fig. 1.

Mov10l1 is specifically expressed in spermatocytes within the testis. (A) Expression of Mov10l1, Mov10, and Mili mRNA in testes of C57BL/6 mice during postnatal development (GEO Series GES640). (B) Mov10l1 mRNA expression in fractions of undifferentiated (undiff.) spermatogonia and spermatocytes (diff.) compared with tubular and interstitial somatic testis cells isolated from testes of 19-d-old C57BL/6 mice (GEO series GES829). (C) Detection of Mov10l1 in embryonic (Upper) and juvenile/adult (Lower) testes by radioactive in situ hybridization with a probe directed against the C-terminal region of Mov10l1; exposure was 3 wk for embryonic and 1 week for postnatal tissue. (Upper Left) A dark-field image of a transverse section through the lower abdomen of an embryonic day 18 (E18) mouse. (Upper Center) An enlargement of Upper Left showing Mov10l1 mRNA as bright white dots in testis. (Upper Right) A high-magnification bright-field image of a seminiferous tubule depicting Mov10l1 as black silver grains localized specifically in gonocytes. (Lower) Detection of Mov10l1 in 7-wk-old adult (Lower Left, dark-field; Lower Center, bright-field) and in P15 juvenile (Lower Right) mouse testis. PS, pachytene spermatocytes; RS, round spermatids; ES, elongating spermatids; SG, spermatogonia.