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Stronger HPV16-specific cytokine production by patients with small VIN3 lesions was observed. Patients are grouped according to clinical outcome (CR or non-CR) and lesion size (smaller or larger than ≤9.5 cm2) at study entry: The strength (median + interquartile range) of cytokine production (A–D) and proliferation at indicated time points (E) is depicted. *0.01 < P < 0.05; **0.001 < P < 0.01; ***P < 0.001. (Exact P values are given in Tables S3 and S4.)
