Table 1.

Targets of Drosophila Orb2RA and Orb2RB

Synaptic growth/stability	Synaptic activity	Proteolysis	Unknown
Neuroligin	N-Syb	Uch	CG30193
Still life	Pka-R2	Rpt1	CG14528
Brain tumor	Widerborst	Rpt4	CG6891
Capulet	Pathetic	Rpn9	CG12769
Glaikit		Unkempt	CG31300
Act5c		Tequila	CG6129
Branchless		Murashka	CG4306
DaPKC			CG10824
Orb2

The targets are grouped based on their known functions either in the nervous system or in other cell types. The cellular functions of these targets are cell polarity and asymmetric growth, DaPKC, widerbrost (a protein phosphatase) (30), glaikit (a phospholipase D) (31), cytoskeleton remodeling, actin5C, capulet (adenylyl cyclase associated protein) (34), still life (Guanine nucleotide exchange factor) (35), growth factors, branchless (FGF) (39), translation regulators, pathetic (amino acid transporter) (38), brain tumor (37), cell-adhesion molecules, neuroligin (40), synaptic vesicle protein n-synaptobrevin (41), regulators of cAMP signaling, PKA-R2, secretory protease, tequila and components of ubiquitin pathway, unkempt (putative ubiquitin ligase) (42), murashka (putative E3 ubiquitin ligase) (14), ubiquitin hydrolase (43), and components of 20S proteosomes rpt1, rpt4, and rpt9 (44).