Table 1.
Synaptic growth/stability | Synaptic activity | Proteolysis | Unknown |
Neuroligin | N-Syb | Uch | CG30193 |
Still life | Pka-R2 | Rpt1 | CG14528 |
Brain tumor | Widerborst | Rpt4 | CG6891 |
Capulet | Pathetic | Rpn9 | CG12769 |
Glaikit | Unkempt | CG31300 | |
Act5c | Tequila | CG6129 | |
Branchless | Murashka | CG4306 | |
DaPKC | CG10824 | ||
Orb2 |
The targets are grouped based on their known functions either in the nervous system or in other cell types. The cellular functions of these targets are cell polarity and asymmetric growth, DaPKC, widerbrost (a protein phosphatase) (30), glaikit (a phospholipase D) (31), cytoskeleton remodeling, actin5C, capulet (adenylyl cyclase associated protein) (34), still life (Guanine nucleotide exchange factor) (35), growth factors, branchless (FGF) (39), translation regulators, pathetic (amino acid transporter) (38), brain tumor (37), cell-adhesion molecules, neuroligin (40), synaptic vesicle protein n-synaptobrevin (41), regulators of cAMP signaling, PKA-R2, secretory protease, tequila and components of ubiquitin pathway, unkempt (putative ubiquitin ligase) (42), murashka (putative E3 ubiquitin ligase) (14), ubiquitin hydrolase (43), and components of 20S proteosomes rpt1, rpt4, and rpt9 (44).