Table 2.
Sedation medication used and dosages n (%)
| Tandem (group A) (n = 54) | EUS only (group B) (n = 56) | P-value1 | ERCP only (group C) (n = 53) | P-value2 | |
| Sedation type | |||||
| Conscious sedation | 52 (96) | 56 (100) | 0.24 | 52 (98) | 0.22 |
| GA/propofol | 2 (4) | 0 | 0.24 | 1 (2) | 0.22 |
| Medications used for sedation | |||||
| Meperidine | 49 (91) | 56 (100) | 0.03 | 44 (83) | 0.27 |
| Midazolam | 54 (96) | 56 (100) | 0.24 | 53 (98) | 1.00 |
| Diphenhydramine | 16 (30) | 4 (7) | 0.003 | 28 (53) | 0.02 |
| Promethazine | 5 (9) | 4 (7) | 0.74 | 0 | 0.06 |
| Fentanyl | 7 (13) | 0 | 0.01 | 8 (15) | 0.12 |
| Total dosage of sedatives used (mean ± SD) (range) | |||||
| Meperidine (mg) | 151.1 ± 64 (25-325) | 104 ± 43.6 (25-250) | < 0.0001 | 104.5 ± 32.5 (25-175) | < 0.0001 |
| Midazolam (mg) | 8.5 ± 3.2 (0-16) | 6.3 ± 2.4 (2-13) | 0.0001 | 6.9 ± 3.4 (0-16) | 0.01 |
| Diphenhydramine (mg) | 50 ± 15.8 (25-100) | 50 ± 0 (50) | 1.00 | 51.8 ± 9.45 (50-100) | 0.64 |
| Promethazine (mg) | 25 ± 0 (25) | 25 ± 0 (25) | 1.00 | 0 | NA |
| Fentanyl (mcg) | 100.0 ± 55.9 (25-175) | 0 | NA | 146.9 ± 54.2 (75-200) | 0.12 |
1
P-value of group A vs group B;
2
P-value of group A vs group C. GA: General anesthesia.