Table 3. Descriptive statistics and hypothesis testing results for pancreas data.
Rows 1–3: Means and standard deviations of spectral parameters for normal pancreas (NP), pancreatic cancer (PC), and chronic pancreatitis (CP) cases from Study 2 (validation study). Row 4: The p-values resulting from ANOVA calculations assuming equal variance between groups. Rows 5–7: The p-values resulting from multiple comparisons using Bonferroni's criterion. Rows 8–10: Means and standard deviations of spectral parameters normal pancreas (NP), pancreatic cancer (PC), and chronic pancreatitis (CP) cases from both studies. Row 11: The p-values resulting from ANOVA calculations assuming equal variance between groups. Rows 12–14: The p-values resulting from multiple comparisons. Bonferroni's criterion was used for slope and intercept, whereas Tamhane's T2 criterion was used for midband fit and R2.
Data Set | B-mode appearance | Midband Fit (dB) | Slope (dB/MHz) | Intercept (dB) | Correlation coeff. R2 |
---|---|---|---|---|---|
Study 2 (Validation Study) | Normal Pancreas (n = 15) | −40.9±3.8 | −1.44±0.31 | −32.2±4.7 | 0.31±0.08 |
Pancreatic Cancer (n = 10) | −53.3±1.2 | −0.94±0.33 | −47.6±2.8 | 0.17±0.05 | |
Chronic Pancreatitis (n = 3) | −49.5±3.3 | −1.28±0.54 | −41.8±6.5 | 0.25±0.10 | |
ANOVA p-value | < 0.001 | < 0.01 | < 0.001 | < 0.001 | |
NP vs. PC p-value | < 0.01 | < 0.01 | < 0.001 | < 0.001 | |
NP vs. CP p-value | < 0.001 | 1 | < 0.01 | 0.59 | |
PC vs. CP p-value | 0.21 | 0.43 | 0.14 | 0.27 | |
Study 1 + Study 2 | Normal Pancreas (n = 40) | −41.5±3.4 | −1.86±0.76 | −30.3±5.4 | 0.40±0.12 |
Pancreatic Cancer (n = 13) | −53.2±1.1 | −0.98±0.31 | −47.3±2.6 | 0.16±0.04 | |
Chronic Pancreatitis (n = 7) | −50.2±2.1 | −1.21±0.34 | −42.8±4.0 | 0.26±0.07 | |
ANOVA p-value | < 0.001 | < 0.01 | < 0.001 | < 0.001 | |
NP vs. PC p-value | < 0.001 | < 0.01 | < 0.001 | < 0.001 | |
NP vs. CP p-value | < 0.001 | 0.055 | < 0.001 | < 0.01 | |
PC vs. CP p-value | < 0.05 | 1 | 0.14 | < 0.05 |